I1774

Sigma

 

Iturin A from Bacillus subtilis

≥90% (HPLC)

CAS Number:64667-10-3
MDL number:MFCD01094135

Related Products

Reviews

Description

Biochem/physiol ActionsIturin A exhibits strong antifungal activity against pathogenic yeast and fungi.1 It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores2 and its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.3
Other NotesA family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.

Properties

assay≥90% (HPLC)
storage temp.2-8°C

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany3

References

Cited Reference1. Klich, M.A., et al. Mycopathologia 127, 123, (1994) Abstract
 2. Maget-Dana, R., et al. Toxicology 87, 151, (1994) Abstract
 3. Thimon, L., et al. Cytobios. 79, 96, (1994)